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- Chaperones also aid in quality control decisions as persistent chaperone binding can help to sort terminal misfolded proteins for degradation. There are two major molecular chaperone families in the endoplasmic reticulum (ER) that assist proteins in reaching their native structure and evaluating the fidelity of the maturation process.DOI: 10.1007/978-3-030-67696-4_3Published: 2021www.ncbi.nlm.nih.gov/pmc/articles/PMC9185992/
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